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| Name |
Petzold, Linda R. |
| Location
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University of California, Santa Barbara |
| Primary Field
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Applied Mathematical Sciences |
| Secondary Field
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Biophysics and Computational Biology |
 Election Citation
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Linda R. Petzold's research focuses on modeling, simulation, and data analytics for multiscale systems in biology, engineering, and medicine.
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Research Interests
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Linda Petzold's research focuses on modeling, simulation and data analytics for multiscale systems in biology, engineering and medicine. She is best known for her pioneering work on the numerical solution of differential-algebraic equations (DAEs). Her software, DASSL and its successor DASPK for the numerical solution of DAEs, are widely used throughout science, engineering and technology. She has also made seminal contributions in the area of systems biology. Much of her work in this area has focused on the development of computational techniques for the discrete stochastic simulation of multiscale biochemical systems. In microscopic systems formed by living cells, small numbers of key reactant molecules can result in dynamical behavior that is discrete and stochastic (random), rather than continuous and deterministic. In simulating and analyzing such behavior it is necessary to employ numerical methods that directly take into account the underlying discrete stochastic nature of the molecular events. She has developed widely used computational software for discrete stochastic simulation, including StochSS Live!. Using these techniques and others, she has made important advances in a wide range of problems from biology and medicine, including Circadian rhythm, unfolded protein response, cell polarization, migraine and trauma.
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