Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Birnbaumer, Lutz
Location Pontifical Catholic University of Argentina
Primary Field Physiology and Pharmacology
 Election Citation
Birnbaumer's contributions are seminal to the understanding of hormone action and membrane signal transduction. Foremost are the co-discoveries of GTP-dependent signal transduction, which is used by over 100 distinct receptors (with Martin Rodbell in 1971), and G protein-regulated ion channels, which exposed an important aspect of modulation of cellular excitability.
 Research Interests
At present Birnbaumer is studying molecular mechanisms that regulate intracellular calcium levels and in collaboration with others the physio-pathological roles of TRPC channels using genetically modified mice he created at UCLA and at the NIEHS as research tools.

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