Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Branton, Daniel
Location Harvard University
Primary Field Biophysics and Computational Biology
Secondary Field Cellular and Developmental Biology
 Election Citation
Not available
 Research Interests
Nanopore Sequencing: A novel technology for sequencing individual DNA molecules using single-channel recording techniques has been conceived. Single molecules of DNA are drawn through a small channel or nanopore that functions as a sensitive detector. The detection schemes being developed will transduce the different chemical and physical properties of each base into a characteristic electronic signal. Nanopore sequencing has the potential of reading very long stretches of DNA at rates exceeding 1 base per millisecond. Thus, the time and errors usually required to deal with repetitive sequences and the assembly of contiguous elements can be minimized.

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