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Name |
Goldstein, Joseph L. |
Location
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The University of Texas Southwestern Medical Center |
Primary Field
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Medical Genetics, Hematology and Oncology |
Secondary Field
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Medical Physiology and Metabolism |
Election Citation
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Goldstein, together with Michael Brown, discovered the low density lipoprotein (LDL) receptor and worked out how these receptors control cholesterol homeostasis. This research laid the conceptual groundwork for development of the statin drugs that lower blood LDL-cholesterol and prevent heart attacks. It also opened the field of receptor-mediated endocytosis. |
Research Interests
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Research interests include medical genetics, cholesterol metabolism, and signal transduction and cell regulation. |
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