Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Spradling, Allan C.
Location Carnegie Institution for Science
Primary Field Cellular and Developmental Biology
Secondary Field Genetics
 Election Citation
Spradling discovered the first example of specific gene amplification in development for protein genes (chorion genes in Drosophila). He revolutionized Drosophila genetics by discovering a method to transform Drosophila with any cloned gene. Transposable element mediated transformation has permitted his identification of cis-acting regulatory sequences for amplification and gene activity.
 Research Interests
My areas of interest are Drosophila genetics, in particular, transposable elements as agents for genetic manipulation; chromosome structure and replication; and oogenesis, specifically, stem cell regulation.

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