Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Beaty, Barry J.
Location Colorado State University
Primary Field Animal, Nutritional and Applied Microbial Sciences
Secondary Field Microbial Biology
 Election Citation
Beaty, an epidemiologist, pioneered the study of the molecular and genetic factors of viruses and mosquitoes that foster the transmission of such deadly diseases as yellow fever, viral encephalitis and dengue. He is also a trailblazer for efforts to genetically engineer mosquitoes so that they no longer harbor disease-causing viruses. His seminal studies suggest exciting new ways to control emerging and resurging mosquito-borne diseases.
 Research Interests
As an epidemiologist I have concentrated on the epidemic and evolutionary potential of arthropod-borne viruses--such as dengue, yellow fever, and the mosquito-borne encephalitis viruses--and of certain rodent-borne viruses. Major research endeavors include developing rapid, clinically relevant diagnostic and surveillance techniques for arbovirus infections in vertebrate and invertebrate hosts; defining vector and viral genetic and molecular determinants of arbovirus transmission, transeasonality, and trafficking; describing vector and virus genetic determinants of the epidemic potential of dengue hemorrhagic fever in Mexico; creating arbovirus expression systems to characterize genes of interest in vectors; and investigating and demonstrating the evolutionary potential of arboviruses in vectors. I have recently investigated the molecular biology and population genetics of insect vectors of pathogens to develop novel strategies for control of these important diseases. The principal emphases are developing molecular mechanisms to transform mosquito vectors, engineering novel pathogen-resistant vector phenotypes, and developing drive mechanisms to drive anti-pathogen effector systems through vector populations.

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