Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Staskawicz, Brian J.
Location University of California, Berkeley
Primary Field Plant, Soil and Microbial Sciences
Secondary Field Plant Biology
 Election Citation
Staskawicz and his collaborators made seminal contributions to our understanding of the molecular mechanisms that underlie the resistance of plants to pathogens that cause disease. He has employed molecular biological techniques to clone the genes responsible for plant-pathogen interactions, thereby providing information that is critical for using genetic engineering for future plant protection.
 Research Interests
The major emphasis of my laboratory is to elucidate the molecular basis of plant disease resistance. This includes understanding the molecular basis of plant-pathogen specificity and the subsequent signal transduction events that are involved in the disease-resistance-signaling pathway. We are currently employing several model systems to clone genes from both the host and the pathogen that specify plant disease resistance. The model systems that we are currently employing include the interaction of Arabidopsis thaliana, tomato, and pepper with several phytopathogenic bacteria in the genera Pseudomonas and Xanthomonas. Our ultimate goal is to genetically engineer plants for disease resistance in such a way as to reduce the use of environmentally damaging pesticides.

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