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| Name |
Warren, Stephen T. |
| Location
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Emory University |
| Primary Field
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Medical Genetics, Hematology and Oncology |
| Secondary Field
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Cellular and Molecular Neuroscience |
 Election Citation
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Warren discovered triplet repeat expansion as a new heritable mechanism of disease and the cause of fragile X syndrome. With
~remarkable focus, he elucidated pathways linking repeat expansion to mechanisms of cognitive deficiency, leading to the recognition of classes of drugs with therapeutic potential, culminating in ongoing clinical trials. |
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Research Interests
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Warren led the international team that discovered the FMR1 gene, responsible for fragile X syndrome, the most common heritable cause of cognitive deficiency. Since that time, his lab has consistently led the field in deciphering the genetics, biochemistry, cell biology and neurobiology of fragile X syndrome. Warren's work has illuminated therapeutic approaches for the treatment of fragile X syndrome, including successful chemical library screens, that have culminated in several ongoing clinical trials. In addition to fragile X syndrome, his laboratory has recently expanded its interest to the genetic determinants of schizophrenia, bipolar disorder, and autism. |
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