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| Name |
Russinova, Eugenia (Jenny) |
| Location
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Ghent University |
| Primary Field
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Plant Biology |
| Secondary Field
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Cellular and Developmental Biology |
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 Research Interests
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Eugenia (Jenny) Russinova's laboratory is interested in the signal transduction pathway that plant cells use to respond to the growth promoting steroid hormones. One aspect of their research is to understand how subcellular compartmentalization and trafficking of receptor complexes influence signaling outcomes. They use high-resolution live-cell imaging, chemical genomics, and proteomics to investigate the subcellular localization, mobility, transport routes and binding interactions of different signaling components. They were able to visualize and track plant steroids in living cells, revealing that plasma membrane is the main signaling platform of the steroid receptors in plant and endocytosis attenuates signaling. They also study how downstream steroid signaling regulators, such as the highly conserved plant Glycogen synthase kinase3 (GSK3)-like kinases, ensure cross talk with other signaling pathways. They have revealed that the interaction between steroid hormones and the signaling pathway controlling stomatal development is enabled by GSK3 scaffold proteins that are linked to cell polarity. |
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