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Name |
Barrangou, Rodolphe |
Location
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North Carolina State University |
Primary Field
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Genetics |
Secondary Field
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Plant, Soil and Microbial Sciences |
Election Citation
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Barrangou is known for key contributions to genomics of Lactobacteria and CRISPR-Cas research. He was the first to experimentally demonstrate the ability of CRISPR-Cas to protect bacteria against bacteriophages. He pioneered functional dissection of CRISPR-Cas guide RNAs and the use of CRISP-Cas for bacterial genome editing. |
Research Interests
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Barrangou is focusing on the characterization of CRISPR-Cas systems, and their applications in bacteria. The CRISPRlab has published numerous studies on the various applications of CRISPR-Cas systems, and illustrated their use for the study and development of probiotics, including for genotyping, phage resistance, and genome editing to understand and enhance health-promoting functions of interest. The work has spanned basic scientific to understand and decipher the genomics of lactic acid bacteria, as well as developing novel technologies and applying them to develop and formulate next-generation probiotic strains.
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