Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Barillas-Mury, Carolina
Location National Institutes of Health
Primary Field Microbial Biology
Secondary Field Animal, Nutritional and Applied Microbial Sciences
 Election Citation
Barillas-Mury's work has revolutionized our understanding of mosquito immune defenses against malarial parasites, including nitration in the midgut that marks parasites for lysis and innate immune memory. Her discovery of a parasite molecule that suppresses nitration uncovered a molecular strategy parasites use to evade immunity and enable their transmission.
 Research Interests
Carolina Barillas-Mury's laboratory is interested in understanding the interactions between the mosquito immune system and Plasmodium parasites that are critical for malaria transmission, with the ultimate goal of disrupting the parasite's life cycle and preventing human disease. Her program has four major areas of interest: Interactions between Plasmodium parasites, the gut microbiota, and mosquito midgut epithelial cells; Immune pathways that mediate antiplasmodial responses; Hemocyte differentiation and innate immune memory in mosquitoes; and Plasmodium evasion of the mosquito immune system

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