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Name |
Devreotes, Peter N. |
Location
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Johns Hopkins University School of Medicine |
Primary Field
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Physiology and Pharmacology |
Secondary Field
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Cellular and Developmental Biology |
Election Citation
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Devreotes has provided the most definitive molecular analysis of chemotaxis, the mechanism by which cells sense their surroundings and move directionally. He was the first to identify chemoattractant receptors and to visualize G-protein activation in living cells. |
Research Interests
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Dr. Devreotes' research focuses on understanding how cells sense their surroundings and move towards chemical stimuli. Chemotaxis is critical for morphogenesis in development, immune cell trafficking, stem cell homing and wound healing, and it is exploited in disease states such as cancer metastasis. Dr. Devreotes was the first to identify chemoattractant receptors and to demonstrate that signaling events occur selectively at the cell's leading edge, studies that have led to the most definite understanding of the strategy that cells use to sense direction. |
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