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| Name |
Bickmore, Wendy |
| Location
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University of Edinburgh |
| Primary Field
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Cellular and Developmental Biology |
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 Research Interests
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Prof. Bickmore is fascinated by the three-dimensional organization of the human genome on chromosomes and in cells and how that influences genome function in health and disease. She discovered that human chromosomes are non-uniformly organized in the nucleus of our cells and, by re-engineering 3D genome organisation and synthetically controlling transcription of individual genes, she has explored the causal role of genome and chromatin organisation in gene activation and repression. Her current research explores how the non-coding genome regulates gene expression, in particular how 3D chromosome organisation allows distant enhancers to communicate with their target gene promoters and the role of protein complexes in shaping genome and chromatin organisation. |
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