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| Name |
Ramakrishnan, Lalita |
| Location
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University of Cambridge |
| Primary Field
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Microbial Biology |
| Secondary Field
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Immunology and Inflammation |
 Election Citation
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Ramakrishnan, using a zebrafish larva-Mycobacterium marinum model of Tuberculosis (TB), has uncovered fundamental mechanisms of TB pathogenesis that are relevant for human disease. Her work has overturned previous dogma concerning TB granulomas and has uncovered previously unknown pathways of human host susceptibility and in vivo antibiotic tolerance. |
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Research Interests
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Lalita Ramakrishnan received her M.B.B.S. from Baroda Medical College in India and her Ph.D. in immunology from Tufts University, Massachusetts, USA. After completing medical residency and clinical infectious diseases training, she did postdoctoral work with Stanley Falkow at Stanford University, California, USA, where she developed Mycobacterium marinum as a model for tuberculosis. She joined the faculty of the University of Washington, Seattle, USA, in 2001, where her laboratory developed the zebrafish model of tuberculosis that has enabled insights into tuberculosis pathogenesis, antibiotic tolerance, and the genetics of host susceptibility to tuberculosis. She is also a practicing infectious diseases physician. In 2014, she moved to the University of Cambridge where she is a Wellcome Trust Principal Research Fellow. |
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