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| Name |
Amara, Susan G. |
| Location
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National Institutes of Health |
| Primary Field
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Physiology and Pharmacology |
| Secondary Field
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Cellular and Molecular Neuroscience |
 Election Citation
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Amara's work has provided molecular insight into the mechanisms that transport and inactivate neurotransmitters, the molecules that pass signals between the nerve cells in our brains. Her pioneering studies of glutamate transporters have revealed that they function as both carriers and ion channels. This work is important for medicine because the transporter proteins for neurotransmitters are the primary targets for amphetamines and antidepressants. |
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Research Interests
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Research in our laboratory focuses on neurotransmitter transporters, the plasma membrane proteins that limit the actions of neurotransmitters following their release from neurons. These carrier proteins catalyze the inward movement of neurotransmitter molecules and have a profound impact on the extent of receptor activation that occurs during neuronal signaling. We have also shown that these transporters can possess a substrate-dependent ion channel-like activity, a property that allows them to |
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