Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Cantor, Charles R.
Location Retrotope, Inc.
Primary Field Biophysics and Computational Biology
Secondary Field Medical Genetics, Hematology and Oncology
 Election Citation
Cantor has made important contributions to our understanding of the solution structure and spectroscopy of nucleic acids, protein-nucleic acid complexes, and cellular organelles. Most recently he has pioneered in the separation and physical mapping of whole chromosomes, including those of the human genome.
 Research Interests
My research is focused on identifying biological problems that are resistant to conventional analytical approaches and then developing new methodologies or techniques for solving these problems. My laboratory has developed methods for separating large DNA molecules, for studying structural relationships in complex assemblies of proteins and nucleic acids, and for sensitive detection of proteins and nucleic acids in a variety of settings. My current interests include the development of new methods for faster DNA sequencing, the development of new variations and analogs of the polymerase chain reaction, and the development of engineered regulatory circuits with novel properties. I am also interested in exploring the possible use of biological molecules for applications of nanoengineering and microbotics and in making detectors capable of recognizing specific single molecules, or capable of performing continuously monitoring in vivo diagnostics.

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