Proceedings of the National Academy of Sciences of the United States of America

About the PNAS Member Editor
Name Walter, Peter
Location University of California, San Francisco School of Medicine
Primary Field Biochemistry
Secondary Field Cellular and Developmental Biology
 Election Citation
Walter is a biochemist who discovered the signal recognition particle, an important part of the protein synthesis apparatus in cells. He has deciphered the fascinating molecular mechanisms that allow this system to mediate the cotranslational targeting of proteins to the endoplasmic reticulum. Walter has subsequently pioneered studies of the "unfolded-protein-response," a new pathway that mediates communication between two separate intracellular compartments - the endoplasmic reticulum and the nucleus.
 Research Interests
The Walter lab seeks a molecular understanding of how cells control the quality of their proteins and organelles during homeostasis and stress. They aim to understand how the rewiring of these processes connects to various diseases, including cancer, diabetes, cognitive disorders, and aging.

 
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